4,4'-Dimethoxytrityl chlorideyog ib pab pawg muaj zog nucleoside thiab nucleotide tiv thaiv thiab tshem tawm tus neeg sawv cev.
Synonym:DMT-Cl
CAS nr:40615-36-9
Cov khoom
Tshuaj Formula
Molecular Luj
Cia Kub
Melting Point
Purity
Sab nrauv
C21H19ClO2
338,82 g / mol
2 ~ 8 ℃
120-125 ℃
≥98%
Paj yeeb Crystalline
Raws li cov khoom tseem ceeb ntawm nucleic acid chains, nucleosides thiab nucleotides ua lub luag haujlwm tseem ceeb hauv kev xa cov ntaub ntawv caj ces.Txawm li cas los xij, vim lawv cov tshuaj reactivity thiab degradation yooj yim, nucleosides thiab nucleotides yuav tsum tau tshwj xeeb reagents los tiv thaiv lawv thaum lub sij hawm synthesis.DMTCl4 'Dimethoxytrityl (DMTCl) yog ib pab pawg muaj txiaj ntsig zoo tiv thaiv thiab tshem tawm tus neeg sawv cev uas tau hloov pauv kev tiv thaiv ntawm nucleosides thiab nucleotides thaum lub sijhawm sib xyaw.
DMTCl yog hydroxyl tiv thaiv tus neeg sawv cev uas xaiv reacts nrog hydroxyl pawg ntawm nucleosides thiab nucleotides thaum lub sij hawm synthesis los tsim ib pab pawg tiv thaiv ib ntus uas tiv thaiv nucleosides thiab nucleotides los ntawm reacting nrog lwm yam tshuaj.Cov pab pawg tiv thaiv ib ntus no tau yooj yim tshem tawm tom qab kev sib txuas, tawm hauv cov nucleosides lossis nucleotides ntshiab.
Vim nws zoo heev reactivity thiab selectivity,DMClyog dav siv los ua pab pawg tiv thaiv thiab tshem tawm tus neeg sawv cev hauv kev sib txuas ntawm DNA, RNA thiab lwm yam nucleic acids.Nws yog qhov tshwj xeeb tshaj yog muaj txiaj ntsig rau oligonucleotide synthesis qhov twg yuav tsum muaj kev tswj hwm ntawm nucleotide txoj hauj lwm thiab ua ntu zus.
Ntxiv rau kev ua haujlwm ua pab pawg tiv thaiv thiab tshem tawm, DMTCl yog lub zog hydroxyl tiv thaiv ntawm nucleosides thiab nucleotides.Nws tiv thaiv pawg hydroxyl ntawm nucleosides thiab nucleotides los ntawm oxidation, txo qis, thiab lwm yam kev cuam tshuam uas tuaj yeem ua rau lawv puas tsuaj thaum lub sijhawm sib xyaw.
Hauv cov ntsiab lus,DMTCl4 4 'dimethoxytritylyog ib qho cuab yeej tseem ceeb rau kev sib txuas ntawm nucleosides thiab nucleotides.Nws zoo heev reactivity, selectivity thiab versatility ua rau nws ib tug zoo tagnrho pab pawg neeg tiv thaiv thiab tshem tawm tus neeg saib xyuas thiab hydroxyl tiv thaiv tus neeg saib xyuas rau DNA, RNA thiab lwm yam nucleic acid synthesis.Yog tias koj xav tau kev tiv thaiv zoo thiab txhim khu kev qha ntawm nucleosides thiab nucleotides thaum lub sijhawm sib txuas, saib tsis pub dhau DMTCl.
Post lub sij hawm: Jun-08-2023